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MetaGraph

©2019-2025 BMI LAB | ETH ZURICH | PRIVACY | IMPRINT

    Petabase-Scale Search for Genomics & Beyond

    Scalable DNA, RNA, and Protein search for biological discovery

    Making Biology Searchable

    MetaGraph indexes and compresses vast collections of DNA, RNA, and protein sequences—representing petabases of data—and lets you query them instantly to turn big data into biological insight.

    read more in the paper

    From Archives to Insight

    MetaGraph unlocks the world’s sequencing archives, transforming data from sources like SRA and ENA into a unified, searchable landscape. Identify whether a sequence has been observed before and trace its biological context.

    start a search

    Powerful and Flexible

    MetaGraph supports both exact and inexact sequence searches, pairing precision with flexibility. Each result is annotated with sample and metadata context, and the open-source framework is ready to run on your own data.

    explore on GitHub

    Database Statistics

    Aggregated view of our comprehensive biological database collection

    Start SearchView DatabasesView Examples
    > Paste your FASTA sequence and search across millions of genomes

    Powerful Search Capabilities

    Everything you need to perform comprehensive sequence analysis across multiple biological databases.

    Multi-Database Search
    Search across assembled sequences (RefSeq, UHGG) and raw sequences databases (SRA/ENA/DRA) simultaneously for comprehensive results.
    Data Enrichment
    Automatic enrichment with geographic, taxonomic, and metadata integrated directly from the MetaGraph service.
    Interactive Visualization
    Rich data visualization with interactive maps, charts, and AI summary for detailed analysis.
    Real-time Processing
    Live job progress updates with Server-Sent Events for immediate feedback on search status.
    Robust Validation
    Comprehensive FASTA sequence validation with detailed error reporting and format checking.
    Global Coverage
    Access to worldwide genomic data with geographic mapping and continental distribution analysis.

    MetaGraph under the hood

    Understand the details of the MetaGraph service.

    Ready to Start Your Search?

    Upload your FASTA sequences and discover matches across our comprehensive biological databases.

    Begin SearchExplore DatabasesView Examples
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    © 2025 MetaGraph. Advancing biological sequence analysis.